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How an NPCF dollar travels

A $2 candygram won't fund a clinical trial on its own. This is how it gets pooled with everyone else's money until it can.

When someone hands us $2 for a candygram, it is reasonable to wonder where the $2 actually ends up. Here is what we can trace.

The $2 goes into our table's cashbox, which our treasurer counts at the end of the day and deposits into our chapter account. At the end of the semester, we transfer the total to our NPCF team page at give.nationalpcf.org/team/774854. Every dollar we raise passes through that page. We do not take a cut. There is no chapter operating budget that skims off the top. The materials for our events come from members, partner clubs, or small school grants, not from the donations themselves.

From there, NPCF pools our team total with thousands of others and allocates it to its research funding mechanism, most of which runs through the Sunshine Project. The Sunshine Project is a consortium of pediatric cancer research hospitals that share data and co-run clinical trials on cancers too rare to attract industry funding on their own. A single hospital cannot run a trial on 14 kids. Ten hospitals together can.

Most of the money goes to things that look boring on paper and matter a lot in practice. Study coordinators who run the trial day to day. Tissue banks that let researchers compare samples across institutions. Statistical support for small-sample trials, which is harder than it sounds when you cannot just recruit another 5,000 patients to reach significance. The hospitals themselves pay for most of the clinical care, but trial infrastructure, which is what actually lets a new treatment get tested at all, often has to come from outside funding. That is the line item NPCF dollars tend to sit on.

The trial then either works or does not. Most do not. That is how research usually goes, and it is part of why pediatric trials are so expensive on a per kid basis. When one does work, the drug or protocol gets published, other hospitals adopt it, and eventually it becomes the new standard of care. Standards of care do not change because of one donor. They change because a trial crossed its endpoint, and the trial happened because the infrastructure existed, and the infrastructure existed because a few thousand people put $2 into a cashbox somewhere.

It's slower and less photogenic than handing a hospital a giant cardboard check, but it's how new treatments for kids get tested. One candygram won't do that on its own. Years of candygrams from every chapter, pooled with everyone else's donations, can help pay for the trial that does.

Support pediatric cancer research

Donate through our NPCF team page, come to one of our events, or tell a friend about us.